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Symbol
Name
ID
Fadd
Fas associated via death domain
MGI:109324
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal thymocyte apoptosis
abnormal T cell proliferation
cecum inflammation
colitis
thymus hypoplasia
enlarged spleen
increased B cell number
abnormal T cell subpopulation ratio
decreased activated T cell number
decreased single-positive T cell number
spleen hypoplasia
enlarged lymph nodes
decreased susceptibility to experimental autoimmune encephalomyelitis
increased susceptibility to parasitic infection
Availability Mouse Genotype
Faddtm1Mpa/Faddtm1Mpa
Mogtm1(cre)Gkl/Mog+  (conditional)
*
Faddtm1Mpa/Faddtm1Mpa
Tg(Vil1-cre)997Gum/0  (conditional)
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Lck-cre)1Cwi/?  (conditional)
*
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Cd4-cre)1Cwi/?  (conditional)
*
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Mx1-cre)1Cgn/?  (conditional)
Faddtm2.1Wnt/Faddtm2.1Wnt
Tg(Cd4-cre)1Cwi/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory